Hadrien works closely with many different types of clients in Belgium's thriving tech, pharma and biotech landscape. From start-ups to multinationals, his advice helps client identify how to success and grow as a business.

Hadrien is an experienced corporate lawyer who specialises in mergers and acquisitions (M&A), venture capital, public offerings, corporate reorganisations, corporate and security law, and corporate finance. In his role as Partner in Osborne Clarke’s Brussels corporate team, he advises on public and private M&As, and acts for clients on a wide variety of transactional matters and restructurings, including setting-up, financing, reorganising, acquiring, or liquidating business ventures, also providing litigation services in these areas. He furthermore supports clients with ECM, prospectus issuance and market abuse advice or disputes.

Hadrien works with clients at the cutting edge of pharma, biotechnology medical diagnostics and medtech. For example, he has been advising OncoDNA, a cancer theranostic company, for several years as their trusted advisor in both M&A and their commercial expansion. Other clients active in biotech, medtech, and medical diagnostics include Sunrise, Kiomed, BioKuris, BioSenic, ImmunXperts, Delphi Genetics, Vesale Pharma, Kitozyme, Gabi Smartcare, Tasso, and BepharBel Manufacturing.

While an unquestioned specialist in the field of life sciences, Hadrien has significant expertise in other areas, including technology, media and communications, and transportation and automotive, again regularly advising on M&A transactions, joint ventures and investment schemes. In particular, he works with technology companies active in Belgium and throughout Europe, helping them with strategic partnerships, investments and acquisitions. For example, he has recently advised RTL Group, P&V Assurances, Audiense, Acapela, Bolt, Cream and Fortino on their acquisitions, sale or investments and Sunrise, Merchery, Greentripper and Greenomy on their financing rounds.

Hadrien is ranked as an Up and Coming Lawyer for Corporate/M&A in Chambers' 2025 European and Global Guides and is noted in the Legal 500 Commercial, Corporate and M&A, Insolvency and restructuring and Industry focus: Healthcare and life sciences sections for his expertise and experience. 

"Hadrien Chef is an increasingly prominent figure in the Belgian M&A market. He is a popular choice for clients seeking transactional assistance in the pharmaceutical and biotech sectors."

Chambers Global Guide, 2025

"Hadrien Chef has the very rare combination of responsiveness and efficacy while managing workload and stress."

Chambers European Guide, 2025

"Hadrien Chef is available, easily reachable and highly involved in the transaction."

Legal 500, 2025

KiOmed

Advised Kiomed on EUR 18 million fundraising round.

AIDOPTATION

Assisted AIDOPTATION in their Belgian spin-off from the US-based Indy Autonomous Challenge, including investments from LRM and Ethias totalling EUR 5 million, with a larger funding round in preparation.

atbtherapeutics

Advised atbtherapeutics in its EUR 54 million series A funding round.

Audiense

Advised Audiense on its sale to Buxton.

Redalpine

Osborne Clarke has advised the European investor Redalpine on its investment in the Series A funding round totalling EUR 15 million in the Belgian LegalTech start-up LegalFly, read more.

Fortino Capital

Advised Fortino Capital in its investment in addactis Group SA, the pioneering Risktech partner for (re)insurers.

Greenomy

Advised Greenomy, a Belgium based sustainable finance technology platform, on the partnership and investment round led by Euroclear.

OncoDNA

Advised OncoDNA on its various investment rounds as well as on the acquisition of its Spanish subsidiary and French listed subsidiary.

Sunrise

Advised Sunrise on their recent fundraising of €17 million to support the roll out of their ground-breaking sleep medical device in Europe and the American market.

Cream Consulting

Supported the shareholders of Cream Consulting, a Brussels based leading IT consulting company, in its sale to the French digital transformation and business advice company, Audensiel for a majority shareholding.

Acapela

Advised the shareholders of Acapela, a Belgium-based leading software developer of text-to-speech programs, in their sale to Tobii Dynavox AB.

BioSenic

Advised the listed company BioSenic on its reversed merger with the French company Medsenic as well as various private placement of shares and convertible bond programs.

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